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Journal of Genetics & Genomic Sciences Category: Genetics Type: Review Article

Recurrent Pregnancy Loss: Proposal for a Novel Diagnostic Protocol with New Molecular Genetics Insight

Carmelo Piscopo1*
1 Medical And Laboratory Genetics Unit, A Cardarelli Hospital, Naples, Italy

*Corresponding Author:
Carmelo Piscopo
Medical And Laboratory Genetics Unit, A Cardarelli Hospital, Naples, Italy
Tel:39 0817472291,
Email:carmelo.piscopo@aocardarelli.it

Received Date: May 19, 2020 Accepted Date: May 21, 2020 Published Date: May 28, 2020

DOI:10.24966/GGS-2485/100018

INTRODUCTION

Recurrent Pregnancy Loss (RPL) is defined as three consecutive Pregnancy Loss (PL) prior to 20 weeks of gestation, about 1-2% of women will be affected [1,2]. Recently, the American Society of Reproductive Medicine (ASRM) has redefined RPL as two or more pregnancy losses [3]. Using this definition, the incidence of RPL is up to 5% of women [1-3]. Different risk factors are associated with RPL, including advanced maternal age, and number of previous miscarriages [1]. Although RPL remains unexplained in about 50% of the cases, gynecological, endocrinological, immuno-hematological and genetical factors have been described.

Citation:Piscopo C, Saccone G, Santangelo C, Iolascon A, Monica MD (2020) Recurrent Pregnancy Loss: Proposal for a Novel Diagnostic Protocol with New Molecular Genetics Insight. J Genet Genomic Sci 4: 018.

Copyright: © 2020  Carmelo Piscopo, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Journal Highlights
  • Human Genetics
  • Plant Genetics
  • Animal Genetics
  • Genetic Disorders
  • Genetic Engineering
  • Molecular Genetics

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