Heavy metal toxicity refers to the detrimental health effects resulting from exposure to metals such as lead, mercury, cadmium, and arsenic. These metals can accumulate in vital organs, causing oxidative stress, enzyme dysfunction, neurotoxicity, nephrotoxicity, and immunotoxicity. Chronic exposure, even at low doses, poses serious risks to human health and the environment. Heavy metals interfere with essential cellular processes by binding to sulfhydryl groups in proteins or disrupting calcium and zinc homeostasis. Populations at risk include industrial workers, individuals consuming contaminated food or water, and those exposed to environmental pollution. Biomonitoring and chelation therapy are critical strategies for detection and management.

Ongoing research focuses on developing novel biomarkers, nanotechnology-based detoxification strategies, and public health interventions. The Journal of Toxicology: Current Research encourages submissions exploring heavy metal exposure pathways, molecular mechanisms of toxicity, biomarker discovery, and mitigation techniques. Insights into heavy metal toxicity are essential for effective risk assessment and environmental health protection.