Degenerative diseases refer to a group of conditions characterized by the progressive deterioration of cells, tissues, or organs over time. These diseases typically involve the gradual loss of function, leading to irreversible damage. Common examples include neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's disease, where neurons in the brain progressively degenerate, affecting cognitive and motor functions. Similarly, osteoarthritis and other musculoskeletal disorders involve the breakdown of cartilage and joints, leading to pain, stiffness, and mobility issues.

Cardiovascular degenerative diseases, such as atherosclerosis, result from the gradual thickening and hardening of blood vessel walls, restricting blood flow. While the exact causes can vary, factors such as aging, genetics, environmental exposure, and lifestyle choices often play a significant role. Though there are treatments available to manage symptoms, degenerative diseases are generally chronic and currently have no cure, highlighting the importance of early detection and preventive measures to slow their progression.