Cancer is a complex group of diseases characterized by uncontrolled cell growth and the ability to invade surrounding tissues and metastasize to distant organs. It arises due to genetic mutations, epigenetic changes, and dysregulation of cellular signaling pathways that disrupt normal cell cycle control, apoptosis, and differentiation. Cancer is influenced by both intrinsic factors such as inherited mutations and extrinsic factors including environmental exposures, lifestyle, and infections. With over 100 known types, cancer remains one of the leading causes of mortality worldwide, affecting diverse populations and organ systems. Early detection, personalized treatment, and continuous monitoring are essential for improving prognosis. Cancer biology research is vital in identifying new molecular targets and understanding tumor behavior, drug resistance, and disease progression.
Advanced technologies like next-generation sequencing and single-cell analysis are uncovering the molecular underpinnings of cancer with unprecedented precision. As therapeutic strategies evolve, integrating knowledge of tumor genetics, host immunity, and the microenvironment is crucial.
The Journal of Cancer Biology and Treatment, we welcome research that provides novel insights into cancer initiation, progression, and therapeutic resistance, especially work that bridges basic science and translational oncology to improve patient outcomes through innovative interventions and comprehensive biological understanding.