Stem cell therapy is a transformative approach in regenerative medicine that harnesses the unique ability of stem cells to self-renew and differentiate into various specialized cell types. This therapy offers promising solutions for repairing or replacing damaged tissues and treating a wide range of conditions, including spinal cord injuries, neurodegenerative diseases, cardiovascular disorders, and autoimmune conditions. Pluripotent stem cells, such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are at the forefront of therapeutic applications due to their ability to differentiate into any cell type. Mesenchymal stem cells (MSCs) are also widely studied for their immunomodulatory and regenerative properties.

Recent advances in tissue engineering, biomaterials, and gene editing technologies have improved the safety, efficacy, and scalability of stem cell-based interventions. However, challenges remain, including immune compatibility, risk of tumorigenesis, and ensuring long-term functional integration. The Journal of Stem Cells Research, Development and Therapy invites high-quality research and reviews on clinical, experimental, and technological developments in stem cell therapy to accelerate medical breakthroughs.