Cardiovascular Risk

Cardiovascular risk is significantly elevated in individuals with diabetes and metabolic disorders, making cardiovascular disease (CVD) the leading cause of morbidity and mortality in this population. Chronic hyperglycemia, insulin resistance, dyslipidemia, hypertension, and systemic inflammation contribute synergistically to the development of atherosclerosis, endothelial dysfunction, and cardiac remodeling. People with Type 2 diabetes have a two- to fourfold increased risk of coronary artery disease, stroke, and peripheral arterial disease compared to non-diabetic individuals. Additionally, metabolic syndrome and prediabetes are also associated with elevated cardiovascular risk due to overlapping risk factors. Risk assessment tools, such as the ASCVD risk calculator and Framingham score, help stratify patients for preventive strategies. Effective cardiovascular risk management involves aggressive control of blood glucose, blood pressure, and lipid levels, along with smoking cessation, physical activity, and dietary improvements. Pharmacological agents like statins, ACE inhibitors, SGLT2 inhibitors, and GLP-1 receptor agonists offer dual metabolic and cardiovascular benefits. Integrating cardiovascular risk management into diabetes care is essential to reduce long-term complications and improve survival outcomes.


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